UCL TRO Drug Discovery Group

Therapeutic Approaches: Small Molecules

Therapeutic Areas of Expertise: Cardiology, Immunology, Infectious Diseases, Neurological Disorders, Oncology, Ophthalmology, Psychiatric Disorders, Pain, Regenerative Medicine

Center/Program Highlights:

UCL Translational Research Office

(TRO) builds on an increasingly vibrant translational culture across the School of Life and Medical Sciences (SLMS) and the wider university community by providing integrated support for translational research, industrial partnerships and drug discovery.

Through working closely with a broad spectrum of investigators, industry partners and external funding bodies, the TRO facilitates the translation of emerging research into therapies, techniques and medical products with therapeutic value. The TRO aims to provide practical help and expertise to investigators wishing to explore the translational pathway for their idea / project and to negotiate the hurdles and barriers that are inevitably encountered during the progression from idea to health benefit.

The TRO also develops strategies for engaging effectively with global and national companies and institutions and responds to corporate and academic needs through networking opportunities, tailored partnerships, projects, and brand-building initiatives.

The Drug Discovery Group (DDG) provides theoretical and practical expertise to support the progression of selected UCL projects. Activities include the assessment of target tractability; development of project, medicinal chemistry, and screening strategies; compound design and synthesis; hit discovery and validation; and hit to lead optimisation. The DDG is based in established labs in the UCL School of Pharmacy and is part of the wider UCL Drug Discovery Cluster. The Drug Discovery group also hosted the Innovative Therapeutics Postdoctoral Training Programme (ITPTP).

Sources of Funding: Industry Partnerships, Disease Foundations, University


Institutional Affiliation(s): University College London

UCL School of Pharmacy,
29-39 Brunswick Square
London, WC1N 1AX
United Kingdom

Center/Program Start Date: 2012

Number of Employees: 5